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Furthermore, reduction of LDH-A by siRNA or its inhibition by small-molecule FX11 inhibited the progression of sizable human lymphoma and pancreatic cancer xenografts (Le et al, 2010).
In the rat EAE model, therapeutic treatment with Syl930 significantly inhibited the progression of EAE and EAE-associated histological changes in brain and spinal cord of Lewis rats.
Further study showed that miR-17~92 miR-17~92 the progressinhibitedC via suppressing theor angiogenesis through targeting multiprogressionngiofenesis-induCRCg genes, TGFBR2, HIF1α, and viaFA in vivo and in vitro.
Caspase-7 may be the most probable candidate, because shRNA specific for caspase-7 inhibited the progression from M to G1 phases [22].
In contrast, over-expression of catalase, an enzyme decomposing hydrogen peroxide, or both catalase and SOD markedly inhibited the progression of atherosclerotic lesions [17].
However, a mixture of the three probiotic strains, L. paracasei DSM 13434, L. plantarum DSM 15312, L. plantarum DSM 15313 (Lacto-mix), successfully inhibited the progression of EAE and significantly suppressed and reversed chronic EAE in diseased animals.
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Pharmacologic inhibition of αvβ6 potently inhibits the progression of primary and secondary biliary fibrosis.
Acetyl-L-carnitine was significantly more effective than tamoxifen in reducing discomfort and inhibiting the progression of the disease.
This therapy improves function and inhibits the progression of the disease [65].
Small molecular chemical activators of Nrf2 can confer protection against oxidative insults and inhibit the progression of diseases related to oxidative stress.
The nitrate ions (from calcium nitrate) formed an oxide layer of Fe2O3 on the steel surface to inhibit the progression of corrosion.
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