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In Giardia trophozoites, introduction of yeast IRNA inhibited the function of GLV-IRES, but the inhibition could be reversed by an over-expression of GILa.
The kinase dead mutations also lead to significantly slower Securin degradation (Fig. 2B), this was likely due to severely mis-localized AurkC-KD protein during mitosis (Fig. 2C) which inhibited the function of APC/C.
The SC decoy-DNAs inhibited the function of the restriction endonuclease, AatII, in a sequence-specific and concentration-dependent manner with an appreciable IC50 value (1.3 μM for SC.DD, 0.016 μM for SC.SD, 0.002 μM for SC.SS).
Compounds 9, 11, and 13 inhibited the function of topoisomerase II more strongly than etoposide with almost same magnitude (around 90% and 30% inhibition at 100 and 20 μM, respectively) which were higher than those of etoposide (72% and 18% inhibition).
We wondered how Hsp70 inhibited the function of RNP complex.
Recent study indicated that miR-21 inhibited the function of tumor suppressor PTEN expression by binding its 3' UTR [4].
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Meanwhile, inhibiting the function of miRNA-21, resulting in cells growth inhibition and apoptotic cells death.
A drug inhibiting the function of the ABL protein has had marked success in treating chronic myeloid leukemia.
It inhibits the function of VEGF165 and functions as a MRI contrast agent.
This study was designed to examine whether gefitinib inhibits the function of Pgp.
Their ability to inhibit the function of B-RAF kinase and intracellular ERK1/2 phosphorylation were evaluated.
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