Sentence examples for inhibited her from inspiring English sources

In the presence of physiological concentrations of 17-β-estradiol, both tamoxifen and the analgesic drug acetaminophen inhibited hER dimerization in an antiestrogenic manner.

In addition, the combination treatment of MP470 and Erlotinib completely inhibited HER family activation, and the downstream signaling pathway PI3K/Akt in LNCaP and T47D cells.

Yet fear always inhibited her ability to act on her anger.

Yet such distractions haven't dimmed her aura or inhibited her range.

He asserted that the morphine, because it inhibited her breathing, was nothing more than a thinly veiled disguise for physician-assisted patient suicide.

The pills she was given inhibited her sexually, although she did make some willful but unsatisfactory attempts to sleep with other men, including me.

For example, a phase Ib study of lapatinib monotherapy in 67 patients [ 36], 50% of whom had breast cancer, showed that lapatinib inhibited HER-2 and EGFR phosphorylation at day 28 of therapy, with consequent reduction in the expression of phospho-Erk1/2, phospho-Akt, and cyclin D1; importantly, it also increased tumor cell apoptosis (by terminal dUTP nick-end labeling [TUNEL]).

Therapeutic strategies designed to target and inhibit HER activation that are in clinical development are reviewed, including examples of both small-molecule tyrosine kinase inhibitors and monoclonal antibodies.

Taken together, our findings indicate that although HER2-VIA shares certain similarities with trastuzumab and geldanamycin in its ability to inhibit HER signaling, it affects HER2 behavior in a manner quite distinct from either trastuzumab or geldanamycin.

Accordingly, β2-M may promote apoptosis by inhibiting HER-2 expression, resulting in inhibition of PI3K/Akt and ERK signaling pathways.

As expected, lapatinib did not inhibit HER-dependent signaling in JIMT-1 cells.