Exact(6)
This accumulation increased levels of H2O2, O2 −, and protein carbonyls, inhibited activities of SOD, GSH-Px, and CAT, and decreased the GSH level in the rat corpus striatum.
After Meena et al. [70] injected rats with TiO2 NPs intravenously, the Ti content in the brain increased, leading to excessive ROS production and MDA, accompanied by inhibited activities of SOD and GSH-Px.
In some reports, kava and kavalactones (major constituents of kava) inhibited activities of cytochrome P450 (CYP) isoforms including CYP1A2.
Incubation of freshly-separated human neutrophils with 10−12 10−6 M (CKPV 2 significantly inhibited activities relevant to the inflammatory reaction.
This suggested that EGCG inhibited activities of secreted MMP-2 but did not affect the expression of MMP-2.
SF also inhibited activities of caspase-8 and caspase-3 compared with the OA model control (P < 0.01).
Similar(54)
Several compounds, studied in detail, induced potassium leakage from fungal cells, caused morphological alterations of fungal cells and inhibited activity of candidal β(1,3 -glucan synthase.
Indeed, 30% of activity was still measured for 10 µM of RAL while this concentration totally inhibited activity in strand transfer and processing assays.
This concentration of MG132 inhibited activity by approx. 90%.
Bopindolol increased sleep during the day and night, but only inhibited activity at night.
As a single agent, novel BTK inhibitor CC-292 had no anti-MM activity in vitro or in animal models but potently inhibited activity of osteoclasts.
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