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We have now investigated whether the RAR can also inhibit the function of Myb proteins themselves.
Some cancer immunotherapies consist of antibodies that bind to, and inhibit the function of, proteins expressed by cancer cells.
To inhibit the function of miR-200c-3p miR-200c-3p miR-200c-3p, inH5N1tors of miR-200c-3p or an NC were transfected into A549 cells before virus infection.
Their ability to inhibit the function of B-RAF kinase and intracellular ERK1/2 phosphorylation were evaluated.
Disrupting the Hsp90 Cdc37 interaction provides an alternative strategy to inhibit the function of Hsp90 for cancer therapy.
Farnesyltransferase inhibitors (FTI℉s) inhibit the function of Ras, a GTPase involved in carcinogenesis and T cell activation.
The results suggested that VKJP1 and VKJP3, specifically inhibit the function of ABCG2 through direct interaction with its substrate binding site(s).
Nerve agents are organophosphates which inhibit the function of the acetylcholinesterase (AChE) enzyme in the hydrolysis of neurotransmitter acetylcholine (ACh) in the human nervous system.
And it can inhibit the function of platelets, which contribute to blood clots.
This concept has received clinical validation by the development of active anticancer drugs that specifically inhibit the function of oncoproteins such as BCR-ABL, c-KIT and EGFR.
At high levels, perchlorate can inhibit the function of the thyroid gland, leading to hypothyroidism in adults.
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