Sentence examples for inhibit replication from inspiring English sources

ICLs are mostly cytotoxic to cells in the S phase, which are actively replicating, because these aberrant DNA structures inhibit replication by stalling the polymerase.

Strategies to disrupt this interaction might be developed to inhibit replication of HCV and other viruses.

Vesicular stomatitis virus N protein-specific single-domain antibody fragments inhibit replication.

SFT was found to inhibit replication of all tested HIV strains.

We show ON uptake via receptor-mediated transfection of a human T-cell line in which the mix-mers subsequently inhibit replication of a clinical HIV-1 isolate.

The anti-replicative strategy aims to induce such a shift in heteroplasmy by mitochondrial targeting specifically designed molecules in order to inhibit replication of mutant mtDNA.

RNA interference has been proposed as an alternative strategy to inhibit replication of drug-resistant viruses that emerge during suboptimal antiretroviral therapy for HIV-1.

The transcriptional changes observed with Gal-3 C. neoformans imply cellular stress, which combined with the observation that this protein disrupts vesicles, leads to the suggestion that its mechanism of action may be membrane damage that is sufficient to inhibit replication of fungal cells.

Therefore, we suggest that targeting the active sites of polymerase molecules is not likely to be the best antiviral strategy, as inactivated polymerases do not inhibit replication of other viruses in the same cell and can, in fact, be useful in RNA replication complexes.

The MDCK assay for cytopathic effect proved that antibodies recognizing the N-terminus of M2e could obviously inhibit replication of influenza A virus (A/wuhan/359/95) and influenza B virus (B/wuhan/321/99) in vitro in a dose-dependent manner, while antibodies recognizing the middle part and the C-terminus of M2e did not show such significant inhibitory activities.

They can also inhibit replication and reproducibility in larger animal studies or human trials, researchers say.  .