Sentence examples for inhibit levels from inspiring English sources

PCI-32765 treatment inhibited Btk autophosphorylation at Y223 as well as phosphorylation of PLCγ, but unlike the case in B cells, did not significantly inhibit levels of phosphorylated ERK.

With regards to dopamine metabolism in the forebrain, microdialysis studies found that acute aripiprazole has no effects on dopamine release in either the medial prefrontal cortex or the striatum, whereas it may strongly increase levels of dopamine extracellular metabolites and inhibit levels of extracellular serotonin metabolites in both regions.

Consistent with these observations, depletion of MP1/p14 did not substantially inhibit levels of active ERK or active MEK in cells on fibronectin, whether or not they were exposed to growth factor (Fig. 2B), whereas UO126 essentially eliminated ERK activity in both control and MP1 siRNA-transfected cells (Fig. 2B).

When the breakdown of acetylcholine is inhibited, levels of the neurotransmitter can return to near normal, and the degeneration of neurons and hence the degeneration of cognitive ability is slowed.

Inhibiting levels of miR-21 increase the levels of PDCD4 3.5-fold [73].

Although the activities of SOD and GSH-Px in the cortex and hippocampus were inhibited, levels of malondialdehyde (MDA; an index of lipid peroxidation) and ROS production remained unaffected [67].

Hence from both our in vitro and in vivo results it is evident that β-sitosterol exhibits chemopreventive potential in DMH induced experimental carcinogenesis by inhibiting levels of β-catenin and PCNA accumulation in colon cancer.

In our study, however, H-8 did not inhibited levels of MUC2 protein and NF-κB p65 protein both in the presence and absence of DCA in SEG-1 cells (Fig. 7a).

When confronted with stressors, the top-down modulation from the PFC to the central nucleus of the amygdala is disinhibited, resulting in multiple mechanisms being activated or inhibited (level II) leading to an increase in HR (level III).

This mechanism, which serves to lower levels of phosphorus in the bloodstream, is significant because high phosphate levels inhibit and low levels enhance osteoclastic reabsorption.

Calcium ion itself has similar effects on the osteoclastic process: high levels inhibit and low levels enhance the effect of systemically acting agents such as PTH.