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Inhibition of these enzymes can inhibit invasion and, therefore, metastasis [ 10].
We tested the protein cofilin because it is vital for maturation of invadopodia, since reduced cofilin expression leads to the formation of less invasive invadopodia, but does not inhibit invasion [40].
The day-of-challenge sera of the FCH/4 challenged groups were analyzed for their ability to inhibit invasion of 3D7 strain merozoites using growth inhibition assay (GIA) (Figure 3, right panel and Table 1).
Inhibition of UPEC binding to bladder cells will potentially inhibit invasion and limit the bacteria's ability to build up formidable numbers within the bladder.
Inhibition of uPAR and MMP9 expression has been shown to inhibit invasion in a glioblastoma cell line [ 26].
For instance, AS can considerably inhibit invasion and metastasis in NSCLC.
A recent study has shown that ART, DHA and AS can inhibit invasion and migration of A549 and H1299 cells via depressed Wnt/β-catenin signaling pathway [91].
Experimental studies have shown that biocrusts inhibit invasion of annual grasses (Belnap et al. 2001b; Serpe et al. 2006; Deines et al. 2007).
Additionally, these structures can provide starting points for the development of antibodies and inhibitory molecules targeting protein protein interactions, with the aim to inhibit invasion.
YK-4-279 did not inhibit invasion by ETS-fusion negative PC-3 cells.
In this study, we investigate whether let-7f acts as a tumor suppressor to inhibit invasion and metastasis in gastric cancers.
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