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Dual catalytic beds were introduced to inhibit excess hydro-cracking of C species in gas oil.
Clinical treatments are needed that can inhibit excess osteolysis in an inflammatory microenvironment.
The T18 phosphorylation could inhibit excess MT nucleation by SPB-associated γ-TuSC in mitosis.
Reduction of iNOS expression by S1P and FTY720-P may inhibit excess of NO thereby allowing normal production of extra-cellular matrix constituents.
As hypothesized for legume and rhizobium symbioses, ERF and WRKY TFs could be involved in the regulation of downstream defense responses to inhibit excess Frankia infection under nitrogen-sufficient conditions.
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Overexpression of Polo or Numb significantly suppresses neuroblast overgrowth in PP2A mutants, suggesting that PP2A inhibits excess neuroblast self-renewal in the Polo/Numb pathway.
It is probable that a balance, with moderately elevated TNF-α in the tissues while inhibiting excess TNF-α in the circulation, would maintain efficient leukocyte recruitment to sites of infection while limiting harmful systemic effects, such as excessive systemic leukocyte recruitment and microvascular leakage [43].
Salvinorin A is capable of inhibiting excess intestinal motility (e.g. diarrhea), through a combination of κ-opioid and cannabinoid (mainly CB1 receptor) receptors in inflamed but not normal gut in vivo.
When this function is inhibited, excess PPIX would lead to trigger DNA damage signals such as pATM, pp53 and γH2AX, which function as downstream checkpoints to ensure that the genetic integrity of ES cells is maintained and/or to eliminate ES cells with damaged DNA from the self-renewal pool.
If transforming growth factor-β signaling is inhibited, excess ductal branching results [ 17].
There are a number of factors which may have contributed to the lack of efficacy of rSOST at inhibiting excess tissue formation in this study, including efficacy of a human recombinant SOST in mice, low stability of rSOST, failure of rSOST to reach joints, or insufficient dosage.
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CEO of Professional Science Editing for Scientists @ prosciediting.com