Sentence examples for inhibit age from inspiring English sources
Hence, since GA also possesses PPAR-γ-activating characteristic, it may inhibit AGE accumulation by enhancing scavenging and clearance of AGEs through sRAGE upregulation.
The underlying mechanism may be related to its ability to stimulate PPAR-γ expression and activation because some of the PPAR-γ agonists like pioglitazone and rosiglitazone under the pharmacological class of thiazolidinedione have been demonstrated to inhibit AGE accumulation in clinical studies [26, 27].
The findings demonstrate that saffron extract is able to inhibit AGE formation in vivo.
Therefore, much effort has been extended in search of dietary plants and fruits that effectively inhibit AGE formation.
For instance, pyridoxamine, has been shown to inhibit AGE formation and the formation of lipid-derived Maillard products; advanced lipoxidation endproducts (ALEs) [ 56].
According to the abovementioned antiglycation mechanisms, RGSE may inhibit AGE formation by decreasing the ROS formation or by scavenging the ROS formed in vitro by auto-oxidation of sugars and/or oxidative degradation of Amadori products.
Inhibition of the mTOC1 signaling pathway has also been shown to inhibit age-related weight gain, decrease aging rate, and delay spontaneous cancer in normal inbred female mice (Anisimov et al., 2011).
It also remains unclear how cellular responses to other stresses might inhibit age-dependent increases in DNA damage and promote longevity.
In this study we investigated the potential of anti-inflammatory and anti-coagulant intervention strategies to inhibit age-related and radiation-induced atherosclerosis.
This phenomenon may be due to altered mechanical factors in the joints with OA, which inhibit age-related bone loss when mechanical stresses are relatively higher [ 51].
Although it is well-established that aerobic capacity is significantly compromised in the RA population [ 8], our data also demonstrate that RA patients do not achieve the physical activity levels required to minimise their risk for developing cardiovascular disease, inhibit age-related muscle loss, improve quality of life and well-being.
