These children have a strong inherited predisposition to the disease.
The Diagnosis: Multiple endocrine neoplasia, or MEN, is marked by a rare inherited predisposition to develop tumors, or neoplasia, in various endocrine glands.
In the last decades of the 20th century, geneticists isolated internal agents genetic variations that cause inherited predisposition to specific tumour types.
One murderer in Georgia is trying to escape the chair on the grounds that he has an inherited predisposition to crime.
Many earlier psychologists took it for granted that imitation was caused by an instinct or at least by an inherited predisposition.
Evidence accumulated since 1955 suggests that very low doses of background radiation probably account for 25percentt or more of a vast group of afflictions that occur because of an inherited predisposition.
E-cadherin/CDH1 gene germline mutations have been recognized in families with an inherited predisposition to diffuse-type malignancy.
Numerous risk factors have been identified, the most prominent involving an inherited predisposition in 10% of cases.
Allelic variants of FcγR genes may influence phagocyte biologic activity, providing a basis for inherited predisposition to disease.
Patients with MSI cancers and healthy individuals affected by Lynch syndrome, an inherited predisposition for MSI cancers, develop specific immune responses against these neoantigens.
The value of identifying women with an inherited predisposition to epithelial ovarian cancer has become readily apparent with the identification of the BRCA1, and BRCA2 genes.
