Sentence examples for inherited predisposing from inspiring English sources

It also provides an archetypal example of how inherited predisposing genetic variants may interact with an environmental influence (smoking) to modulate individual cancer risk.

It is estimated that inherited predisposing genes will cause 150-320 cases of breast and 20-40 cases of ovarian cancer each year.

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited cardiomyopathy, predisposing patients to ventricular arrhythmias and sudden cardiac death.

Nigeria may thus typify one of the ancestral populations that harbor inherited genes predisposing African-Americans to high-risk prostate cancer.

Moreover, participants who did not worry much about their own PCT were anxious about whether their children and grandchildren had inherited the predisposing gene.

Hereditary nonpolyposis colorectal cancer (HNPCC) is the most common inherited syndrome predisposing to colorectal cancer (CRC), accounting for 5 10% of the total CRC Lynchh and de la Chapelle, 1999; MIM 114500).

Hereditary non-polyposis colorectal cancer syndrome (HNPCC) is an autosomal-dominant inherited disorder predisposing to colorectal cancer (CRC) and several other cancers at an early age, including endometrial carcinoma.

These mutations are often inherited and predispose people bearing them to sudden death syndrome at a young age.

BRCA1 inherited mutations predispose to high risk of breast and ovarian cancers.

At one end of the spectrum are women who have inherited a predisposing mutation which vastly increases the risk of breast cancer and who develop it at early age.

LKB1 is frequently mutated in Peutz-Jeghers syndrome (PJS), an autosomal dominant inherited cancer predisposing patients to the development of tumours mainly throughout the gastrointestinal tract.