Sentence examples for inherited phenotypes from inspiring English sources

HSP90 can suppress the phenotypic consequences of existing genetic polymorphisms [5], [6], affect epigenetically inherited phenotypes [7], and facilitate the spread of novel mutations [8].

Recent studies have focused on how CNV in the human genome affects various inherited phenotypes, including disease susceptibility [22], [23].

Many inherited phenotypes and behaviors are restricted to a narrow range of species, and are not available or difficult to study in the sequenced models.

The genomes of eukaryotic organisms are rich with polymorphisms (Durbin et al. 2010) that can attenuate gene activity and underlie inherited phenotypes.

Epigenetics refers to the study of epigenetic traits, defined as "stably inherited phenotypes resulting from changes in a chromosome without alterations in the DNA sequence" [ 58].

DNA methylation is considered to be one of the more stable chromatin modifications and one of the few, which once newly established, may even contribute to multi-generationally inherited phenotypes and pathologies [ 11].

Allelic to EVC is the milder autosomal dominantly inherited phenotype Weyers acrodental dysostosis.

By definition, epigenetics is explained by DNA methylation status and modifications of histone proteins within the nucleosomes, allowing an inherited phenotype not linked to changes of DNA sequence.

The consensus modern definition of an epigenetic trait is " a stably inherited phenotype resulting from changes in a chromosome without alterations in the DNA sequence".

An example of where such an approach is valuable is a dominantly inherited phenotype with age-dependent penetrance, but fully penetrant otherwise.

MUTYH germline mutations cause the recessively inherited phenotype: MUTYH-associated polyposis (MAP, MIM #608456), via somatic G C > T A mutations in APC and KRAS [ 1– 3].