Sentence examples similar to inheritance of variants from inspiring English sources

In this report we describe the evolution of antibiotic resistance in bacteria mediated by the epigenetic inheritance of variant gene expression patterns.

Predictions using this methodology currently rely heavily on data from co-segregation in families and from co-inheritance of variants with known pathogenic mutations in the same gene.

As biological data regarding the inheritance modes of variants become available, a biologically justified strategy for incorporating each susceptibility variant can be applied.

One way to assess the genetic susceptibility of rare variants is to look at the inheritance of the variants in the families.

The significance of the association, which was p = 2.0 × 10−5 for novel LOF, increased to p = 4.1 × 10−6 for LOF and deleterious missense variants combined, and augmented further after accounting for segregation and de novo inheritance of rare variants (joint p = 2.3 × 10−7).

Presenilins received early attention due to genetic studies showing that rare, early-onset autosomal dominant forms of familial Alzheimer's disease (AD) are caused by the inheritance of gene variants of this enzyme [13].

Inheritance of genetic variants at one or more loci results in reduced DNA repair capacity.

Stable inheritance of epigenetic variants has been demonstrated in plants [ 7, 13, 27, 28].

From the inheritance of the variants a high-density genetic linkage map can be constructed.

Environmental factors have been shown to promote the epigenetic transgenerational inheritance of phenotypic variants (Skinner et al. 2010).

The effectiveness of selection procedures utilising genomic information can be increased by correctly identifying the mode of inheritance of desired variants.