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L-2-hydroxyglutaric aciduria (L2HGA) is a rare neurometabolic disorder with autosomal recessive inheritance, associated with accumulation of L-2-hydroxyglutaric acid (L-2-HG) in urine and mutations in the L2HGDH gene.
Therefore, for the current classification, microcephalies are classified based upon inheritance, associated clinical features, and causative gene.
Recent work published by our group found that the prolonged lag phase is accompanied by defects in mitochondrial distribution and inheritance associated with increased mitochondrial oxidation [ 38].
Transgenerational inheritance associated with mechanisms other than DNA sequence variation (i.e., epigenetics, parental effects or "cultural inheritance") is thought to affect evolutionary dynamics [ 152].
The majority of FMF patients have autosomal recessive inheritance associated with mutations in the MEFV gene, which encodes pyrin protein [ 1].
These authors, studying of the mode of inheritance associated to the resistance against Phytophthora gummosis in Poncirus trifoliata, identified three quantitative trait loci associated to the resistance against Phytophthora gummosis in citrus, indicating the quantitative pattern of the disease.
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The Q2O project demonstrated how to pull these documents together though one should note that the descriptions in Q2O were SensorML 1.0 while SensorML v2.0 provided significant improvements to support inheritance of associated SensorML through use of the 'typeOf' association.
The inheritance properties associated with this phenomenon were examined.
In addition, a more complex inheritance pattern associated with oligogenic predisposition and possible environmental effects is also possible.
In order to grasp the full spectrum of phenotypes, we did not apply exclusion criteria regarding electrophysiology, inheritance pattern, associated clinical features or neuropathology.
The traditional strength of the Xiphophorus experimental model involves the non-biased assessment of genetic inheritance patterns associated with complex phenotypes within intact animals.
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