To distinguish if the tolerant strains have adapted to aneuploidy or if non-W303 strains can inherently accommodate chromosome amplification, we selected aneuploid derivatives of several naturally euploid parents (see 'Materials and methods').
Mr. Coppola, who will serve as an executive producer, said, "The book is inherently difficult to adapt to the screen, and we've never quite found the right combination of director and writer to do it justice until now".
What's proven more difficult is inventing robots that can act as we do - in other words, that are able to inherently understand and adapt to their environment," he said.
To date, GC/MS- and LC/MS-based high-throughput methods have been inherently difficult to adapt to the screening of isoprenoid-producing microbial strains due to the need for extensive sample preparation of these often highly lipophilic compounds.
Networks are inherently dynamic, constantly adapting to new challenges and opportunities.
For example, cultural probes are inherently playful and ambiguous in nature and need to be re-designed and adapted to the cultural settings in which they are used, which has previously relied on the skills of a professional designer [ 28].
Our recombinant system inherently supports the expression and delivery of various epitopes [ 8, 9, 13] and could be readily adapted if important, new peptides were identified.
