Sentence examples for inherent sequence from inspiring English sources
The hypothesis of this study is that inherent sequence and structural signatures in cellular mRNAs determine their sensitivity to cap-binding protein eIF4E-mediated increase in translation efficiency.
While a high-resolution CT acquisition can be performed in less than a minute, a high-resolution MRI usually requires up to hours depending on inherent sequence parameters, magnet field strength, etc.
Due to the inherent sequence redundancy between RTE loci, assigning piRNA targeting to specific loci is problematic.
This suggests that the inherent sequence specificity of Cas1 is a major determinant of the adaptation process.
The binding profiles of ATF4 and C/EBPβ in hMSCs can be explained by the inherent sequence specificities of the homo- and heterodimeric complexes.
DNA methylation is catalysed by three active DNA methyltransferases (DNMTs), none of which has significant inherent sequence specificity beyond the CpG dinucleotide, implying that their targeting to particular genomic loci must be achieved by other means.
Our experiments using the naïve libraries suggested that aptamer binding to fibrils reflected an inherent, sequence-independent affinity of ribo-oligonucleotides for the fibrillar structure of proteins.
The biases can be attributed to genomic copy number, inherent sequencing bias, plausible mapping ambiguity, and cell-type specific chromatin structure.
It is also evident from the raw data that the constitutive junctions, which might be expected to have similar counts, instead display large variations due to inherent sequence-based probe effects.
Consistent with recent reports [ 35], this illustrates the need for a proper calibration for inherent sequencing bias.
In addition to inherent sequencing chemistry concerns, low coverage sequencing can suffer from read coverage limitations, creating false negative data because the SNP calling software will discard significant proportions of legitimate SNPs due to low coverage.
