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Our systematic study provides detailed insight into the relationships between mutation, protein structure, protein stability, and epistasis and quantitatively depicts the different costs inherent in the evolution of new functions.
The sex chromosome dosage problem is inherent in the evolution of sex chromosomes, an event that has occurred many times during the course of evolution (Larsson and Meller 2006; Vicoso and Charlesworth 2006; Gurbich and Bachtrog 2008; Stenberg and Larsson 2011).
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It is inconsistent to invoke this idea, which attempted to minimize the amount of evolutionary work done by fortuitous chance, while at the same time allowing for an unspecified number of originally neutral mutations to play an inherent role in the evolution of adaptation, as is currently done for example in the case of de novo genes.
They are all, therefore, to be apprehended as histrionic elements which are 'in character' and 'dramatically appropriate,' for their inherent interest as stages in the evolution of an artistically ordered ... experience of a credible human being.
This variable granularity in the similarity-to-function relationship among protein families appears to be inherent to the evolution of protein sequences.
Although there is an inherent interest in understanding the evolution of these other regulatory elements, in the absence of effective computational approaches, the prevalence of compensatory mutations within such elements remains unclear.
These studies together span a range of conclusions, from high transcriptomic conservation at one end, to relatively low conservation in others, suggesting inherent constraints as well as flexibility in the evolution of gene regulatory networks [ 23].
So far in the evolution of the human being, worth has not been considered inherent.
My inherent assumption is that characters present at these stages are fundamental to the body plan, less labile, and thus the changes they undergo throughout evolution represent the major steps in the evolution of the body plan.
In contrast, the evolution of HA in nature is shaped by a combination of HA's inherent mutational tolerance and external selection pressures.
In Pictures: The Evolution of E-books.
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