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Human umbilical cord stem cells have inherent differentiation capabilities and potential usefulness in regenerative medicine.
Mesenchymal stem cells secrete various bioactive factors, have inherent differentiation potential, and modulate angiogenic and growth factors in the local microenvironment [8, 9, 10].
This may at least partially reflect their inherent differentiation potential and could, in analogy to emerging studies in other tissues, possibly indicate their in vivo capacity.
Genetic differentiation studies showed inherent differentiation and infrequent gene flow between IYSVBR and IYSVNL genotypes corroborating the geographical confinement of these genotypes.
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Moreover, randomly integrated transgenes are often subject to pleiotropic position effects as a consequence of epigenetic changes inherent in differentiation, undermining applications in iPSCs.
The assessment of the environmental fate of chemicals and the inherent spatial differentiation requires the use of multimedia models at various levels of complexity (from a simple box model to complex computational and high-spatial-resolution models).
Therefore, endogenous Oct4+ stem cells might either display inherent multipotent differentiation potential or serve as a source for minimal modification approaches to generate iPS with high efficiency.
He postulated that reality is a self-unfolding of dynamic structures or templates ("Begriffe"); as the external contrasts of these templates arise, they are reflected in a continuous internal differentiation inherent to the templates, thus creating further external contrasts, with the result of an increasingly interrelated web of dynamic dependencies.
Because of the complicated nature of numerical solution, deficiencies in the experimental data, and uncertainty inherent in numerical differentiation, among others reasons, the model equation and its approximate linearized version are not convenient for engineering analysis of industrial high pressure filtration cycles.
A recent study has suggested that traditional data analyses for flow cytometry may obscure the underlying continuity of phenotypes that is inherent in cellular differentiation [ 29].
However, the lack of on-line sensors for this purpose and the inherent problems with numerical differentiation make observers indispensable.
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