In conclusion, inherent properties of Treg cells expressing TCRs shared with naive T cells like efficient recruitment, expansion and/or upregulation of Foxp3 are responsible for the predominance of adaptive Treg cells in tumors.
Together, these various studies point to the many fallacies inherent in the conclusions drawn from the NB literature, and they question the role proposed for NB in disease pathogenesis.
LORD STEYN -- It is inherent in this stark conclusion that there is no or virtually no line to be drawn.
Additionally, subgroup analysis has inherent limitations and the conclusion that Ertl subjects have a higher return to duty rate was obtained in this fashion.
Indeed, this conclusion was inherent in the earliest experiments that pointed to the specific immunogenicity of tumors (see [11] for review).
Conclusion: Suffering is inherent in our existence.
(275) Overall, the observations described above lead to the conclusion that the inherent polymorphic nature of Aβ assemblies can be associated with different toxic behavior.
In conclusion, despite the inherent limitations of this model, the analysis suggests that a 65-year-old cohort vaccination programme with PCV13 in Spain would avoid a large number of cases of pneumococcal disease over a 5-year period and would be a cost-saving measure from a healthcare system perspective.
Even randomized trials, however, can produce misleading conclusions because of inherent weaknesses or bias in study design, analysis, and interpretation.
The companion paper details the application of the new approach to progressive collapse assessment of real steel-framed composite multi-storey buildings, making in the process important conclusions on the inherent robustness of such structures and the adequacy of current design provisions.
Inherent to our findings and conclusions, it is important to acknowledge some limitations of our study.
