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Guck, J. et al. Optical deformability as an inherent cell marker for testing malignant transformation and metastatic competence.
This suggests using optical deformability as an inherent cell marker for basic cell biological investigation and diagnosis of disease.
Among the various electrochemical energy storage options under consideration, rechargeable lithium sulfur (Li S) batteries remain the most promising platform for reversibly storing large amounts of electrical energy at moderate cost set by the inherent cell chemistry.
Based on that, and considering the ability of EVs to cross natural barriers (such as membranes), their inherent cell targeting properties, and stability in the circulation, the utilization of EVs as drug delivery system has gained scientific interest.
This suggests the possibility of using optical deformability as an inherent cell marker for basic cell biological investigation, diagnosis of disease, and sorting of stem cells from heterogeneous populations, obviating the need for external markers or special preparation.
Inherent cell heterogeneity and asynchronous differentiation complicate population analysis; therefore, single-cell analysis was employed to determine how changes in cell stiffness correlate with changes in molecular biomarkers during differentiation.
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Standard techniques average the responses of cell populations and thus obscure inherent cell-cell heterogeneity and restrict the ability to distinguish between the individual responses of different cells within a sample[1], [2], [3], [4], [5], [6], [7], [8].
Decoding the complexity of multicellular organisms requires analytical procedures to overcome the limitations of averaged measurements of cell populations, which obscure inherent cell-cell heterogeneity and restrict the ability to distinguish between the responses of individual cells within a sample.
Since these cytokines are important for sustaining memory (IL-2) and mediating effector function (IFN-γ), this analysis provides a snap shot of the quantity and quality of the inherent cell-mediated immunity in relation to viral load in the three different groups of monkeys studied.
High levels of Bcl-2 in cancer cells increase even further the inherent cell-to-cell variations in cell fate, increasing the likelihood of fractional cell killing.
The usage of distinct cells lines allows the analysis of the effects of potential and inherent cell-type selective factors or differential expression levels of ectopic proteins in the subcellular co-localization and targeting of the RPGR-RPGRIP1α1 complex and expression of mutations therein.
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