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In vitro dissolution of MR diclofenac sodium pellets containing 100 mg active ingredient was evaluated under simulated pre- and postprandial conditions using USP Apparatus 3 (reciprocating cylinder, Bio-Dis) and 4 (flow-through cell) and results compared with compendial methods using USP Apparatus 1 (basket) and 2 (paddle).
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Several transition bimetallic sulphide catalysts (with Ru as a constant ingredient) were evaluated in a fluidised bed reactor operated at 160 kPa and 883 1003 K.
The aptitude of seven functional ingredients was evaluated by applying the tensile strength test on cooked noodles.
A series of 28 diverse feed ingredients was evaluated for AV using a mixture design, with 85 combinations of ingredients: 100% of each ingredient (n = 28); 50% of each ingredient and an equal mixture of all others (n = 28); equal mixture of all ingredients, excluding one (n = 28); and an equal mixture of all ingredients (n = 1).
Of these, 9 out of 42 (19.8%) tablets did not meet the tolerance limits set by USP for pyrimethamine and this should be considered conservative since only one of two active ingredients was evaluated.
Twelve commercial pyrethroid insecticides (technical-grade active ingredients) were evaluated individually for acute neurobehavioral manifestations of toxicity under conditions suited to assist with determining whether they act by a common mechanism of toxicity.
"Consumers can be assured that the fragrance used in their favorite products is safe," Solovyov said, noting that individual ingredients are "evaluated for consumer and environmental safety" and that products are "tested according to all government and company-specific requirements".
The structures of all remaining active ingredients were evaluated for the presence of amine and amide functional groups and were checked for any additional published evidence of nitrosatabilty using Medline and Internet sources.
The effect of each ingredient on the chemical composition was evaluated using a 23−1 fractional design.
In addition, the suitability of Raman spectroscopy as verification method for the active pharmaceutical ingredient (API) concentration in solid dispersions was evaluated.
The potential use of this leftover as a substrate ingredient for Flammulina velutipes (F. velutipe) cultivation was evaluated.
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