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Avastin also has serious, if infrequent, side effects, some of which can be lethal.
Infrequent side effects are movement disorders, tics, rash, weight loss, and growth retardation in children.
Safety and tolerability studies of iron carboxymaltose show infrequent side effects [ 14– 16].
Topical preparations of BHC are usually well tolerated, with infrequent side effects. 2 Absorption through the skin and mucosa is low, whereas experimental data indicate that BHC is rapidly absorbed in the gastrointestinal tract.
The removal of respondents who reported rare or very infrequent side effects from the sample resulted in an essentially normal distribution (skew = -.13, <4% of scores at ceiling value).
However, we believe that norfloxacin may be preferred over ciprofloxacin, since norfloxacin has low systemic absorption [ 24] and therefore, may have infrequent side effects and may be safe particularly during pregnancy.
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At the 2010 Breast Cancer Symposium in October, a notable 10-year analysis found that the risk of bone fractures, an infrequent side effect of Arimidex, decreased after women stopped taking the medication.
Whereas a transient benign cough is common, bronchospasm is a more severe, albeit infrequent, side effect that has been reported to occur during antibiotic nebulization [6, 34, 40].
Fried's wife, Diane, suffered an infrequent side effect of mental confusion and delirium from ofloxacin (Floxin), samples of which were inappropriately given to her by gynecologist for a urinary tract infection.
Another known, but rather infrequent, side effect of capecitabine and related drugs is cardiac ischaemia.
As it is thought to be an infrequent side effect and not currently tested for in routine practice, it is not reported in large phase III studies either (Cassidy et al, 2008).
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