Previous studies have documented infrequent hybridization at the end of the ring.
However, its use has been limited because of the documented infrequent, but serious side effects such as agranulocytosis.
Fruit bats of several species serve as reservoir hosts for LBV, with infrequent spillover infections documented in dogs, cats, and a mongoose (37).
Two studies of ZFNs that used unbiased methods to identify off-target genomic sites for several ZFN pairs documented infrequent off-target effects at numerous loci in a cultured human tumor cell line (Gabriel et al., 2011; Pattanayak et al., 2011).
However, communication between providers discharging patients from the ICU and providers admitting these patients to general care units has been documented to be infrequent, incomplete and of poor quality.
The clinical outcomes of cases and controls are shown in Table 3. Within 3 days after initiation of antifungal therapy, documented clearance of candidaemia was significantly infrequent in cases (p = 0.035; Table 3).
Vibrio spp. infections are rarely documented in cancer patients and they are infrequent in solid tumours [ 11].
Female hybrid sterility following Haldane's rule [ 41] would be expected to prevent introgression of mtDNA, although limited fertility of female hybrids has been documented and would provide a route for infrequent introgression [ 41].
An important clue comes from the fact that while examples of ancient and 'recent' HGT events involving chloroplast DNA have been documented [ 2], such events appear to be very infrequent [ 6].
The observers in this study documented frequent communication between physicians and nurses, but weak communication (infrequent) by other types of clinicians that interacted with the clinicians being observed [ 24].
