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To avoid a bias due to infrequent execution paths, discovery algorithms strive for a balance between over-fitting and under-fitting regarding the originating log.
We applied a 'strict' criterion to minimize the possibility of false positives arising from sequencing error and a 'relaxed' criterion to maximize the discovery of relatively infrequent alleles.
We conclude that although coding mutations of Caspase-9 and DFF45 are infrequent in neuroblastoma tumours, our discovery of a rare allele in two neuroblastoma cases should be taken to warrant further studies of the role of DFF45 in neuroblastoma genetics.
For women with germline mutations in breast cancer susceptibility genes, particularly BRCA, the cancers are likely to be of high grade, and the discovery of DCIS is infrequent [ 21].
Infrequent travelers can quickly find transportation options.
As a result, many studies to date have used only a fraction (say 500 sequences) of the available ChIP-seq peak regions for motif discovery, greatly decreasing the chances of discovering motifs for infrequent cofactors.
These landmark studies have identified infrequent driver mutations that are potential targets for therapeutic intervention with approved or investigational drug treatments, among other important discoveries.
PROFANITY -- Mild and infrequent.
PROFANITY -- Infrequent but strong.
Doors are infrequent.
It is very infrequent.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com