Such involvement is infrequent in measure development, especially in younger ages.
Mutating Hras at Q61 leads to papilloma development and infrequent malignant transformation to SCCs (Abel et al., 2009).
Since rpk1 effects are relatively infrequent, the following normal development (due to redundancy of RPK1 function) could compensate for one or few defective cells.
These results suggest that β- and γ-catenins are infrequent mutational targets during development of human lung, breast, kidney, cervical and ovarian carcinomas.
Despite having a dramatically larger surface area than the large intestine, the small intestine is an infrequent site for the development of adenocarcinoma.
During southern winter months the post-sunset ESF development is relatively infrequent over South America due to the generally weaker intensity of the sunset zonal electric field, which, however, is critical in determining the equatorial spread F (ESF) development under magnetospherically disturbed conditions.
The hypothesis that communities located at high altitude are prone to unstable, infrequent parasite exposure limiting the development of functional immunity before adulthood (8, 9, 30 ) is, therefore, not reflected in our data.
The genetic polymorphisms are neither necessary nor sufficient for disease development because they are too infrequent and the associated risk is low; however, they indicate that these pathways are of importance in rendering an individual susceptible to RA development.
However, the development of tumours at this location is infrequent.
This binary classification may be sufficient for assessments of infrequent cases or at the early stages of clinical development.
