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Most significant regions occur near chromosome ends or centromeres where recombination is infrequent, consistent with these regions harboring unconditionally deleterious alleles impacting longevity.
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DNA sequencing results indicated that p53 gene mutations in this series of cPNETs were infrequent, which was consistent with the findings from other studies (Saylors et al, 1991; Adesina, 1994) and could explain the high sensitivity of medulloblastoma cells to radio therapy (Chang et al, 1969).
Therefore, in this paper, we have included a fourth risk category which we have termed the 'abstainers', but we emphasise that the individuals in this category may not necessarily be teetotallers but consistent infrequent drinkers, 31 and therefore there may be some overlap between this group and the lower risk drinkers.
Changes in routine safety laboratory tests were infrequent and without any consistent pattern, and there was no evidence of immunogenicity or significant changes in T cells, immunoglobulins, or autoantibody levels.
The Nc had a fronto-central maximum and was larger for novel than frequent or infrequent stimuli, results also consistent with prior studies (Ackles and Cook, 1998; Courchesne et al., 1981; Stauder et al., 2006).
In this study, we present evidence of infrequent trading in the CCX, consistent with emerging markets that are inhabited by non-competitive agents trading permits.
In our study, evidence of the capsid protein p24 was infrequent (12/215 [6%]) but consistent with the concept that, in some humans, BLV could be replicating.
While disruptions to the myotendinous junction are not thought to be common in patients with ACTA1 mutations, the recessive ACTA1 V154L mutation results in a dystrophic phenotype, alongside Z-disk streaming and infrequent nemaline bodies [ 33], consistent with dystrophic disruption to this structure.
In addition, the elevation of acute inflammatory responses was infrequent and mild, which is consistent with some of the previous reports [ 1, 14].
The patterns of egg production also differed among the '6 × 6' colonies, and they included a cyclical output, a consistent daily output, an infrequent egg output with intermittent days of very high egg output, and an output with no obvious pattern.
Infections rates of 15% of observed labour and births and 5% on record reviews were consistent with random and infrequent hand washing.
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