Key scientific issues regarding possible approaches to synthesize epidemiologic data in informing the hazard characterization of TCE include the following: Use of meta-analytical techniques to summarize epidemiologic findings, including methods for classifying and weighting studies.
Here, we review current understanding of the molecular properties of CARs, how this knowledge informs the rational design and characterization of novel receptors, the successes and shortcomings of CAR-T cells in the clinic, and emerging solutions for the continued improvement of CAR-T cell therapy.
Our understanding of autophagy has been largely informed by the characterization of the yeast system, although increasing interest in mammalian autophagy has driven a series of recent discoveries [6], [18], [19].
What word informs the pear?
It is crucial to compile the relevant information about the different types of uncertainties to inform the process of risk characterization.
In addition, the study results can be used to inform the design of exposure characterization strategies in relevant environmental epidemiology studies in the future.
The generation of these reagents has enabled kinetic and structural characterization to inform the design of potent and selective inhibitors of the JAK family.
The challenge for application at field sites then becomes appropriate site characterization to inform the models, capturing the style of the low permeability zone geometry and incorporating reasonable hydrogeologic parameters and estimates of source history, for scenario testing and more accurate prediction of plume response, leading to better site decision making.
The giggling, scatological misfit that Mozart in many ways actually was is not a difficult role, but McNall informs his characterization with enough inventive detail to give it a forthright reality.
In addition, characterization of the physicochemical properties should inform the toxicologic testing process.
