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The study protocol was approved by the Memorial University Ethics Committee and informed written permission was obtained from parents/guardians.
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Subjects provided informed written consent, and child subjects were required to have written permission and informed consent from a parent or legal guardian.
All experiments were run with the permission of The University of Bradford's ethics committee after gaining informed, written consent from all observers (in accordance with the Declaration of Helsinki).
Ethics permission for the study was obtained from the King Edward Memorial Hospital Ethics Committee and informed written consent was obtained from all participants.
Appropriate ethics permission had been obtained by both groups and twins gave informed written consent at both time points of the study.
Permission for the research was also obtained from hospital management and all participants gave informed written consent to be interviewed or surveyed.
Informed written consent is obtained before inclusion.
All subjects gave informed written consent.
All patients provided informed written consent.
All participants provided informed written consent.
All provided informed written consent.
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