We do not yet know whether prophylactic bisphosphonate therapy would be effective in preventing Paget's disease, however, we envisage that the results of the present study would be used to inform the rationale of a randomised controlled trial to investigate the efficacy of prophylactic bisphosphonate therapy in people with SQSTM1 mutations.
The result, ironically, will be to leave most observers less well informed about the rationale for monetary policy decisions.
The board was informed of the rationale for using the Whitewing, LJM, and Raptor transactions, and after approving them, received status updates on the entities' operations.
Includes mechanisms to ensure participants are fully informed about the rationale for the trial.
Subjects were not informed about the rationale of the study, to prevent a placebo effect of IPC.
Includes mechanisms to ensure that legal guardians and participants are fully informed about the rationale for the trial.
In the two-day event, the participants were informed on the rationale for the study, the protocol, and the data capture forms.
Ethics committes and study participants need to be better informed of the rationale for the use of placebo, along with the associated risks.
Staff were well informed about the rationale for sperm banking and had relatively easy access to large well-established sperm banks.
In addition participants were informed of the rationale for the study, the voluntary nature of the questionnaire and the anonymity of their response with informed consent being given by return of the questionnaire.
