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The rationale for using a conservative estimation of NTHi pneumonia incidence was informed by the considerable variation amongst estimates reported in the literature [ 30- 34].
The assumption of our Bayesian approach is that the final estimations, informed by the raw data, covariates and regional hierarchy, are closer to the 'truth' than any isolated datapoint.
Furthermore, although GLM model specifications could be informed by the data (Blough et al., 1999), the estimation for the link and variance and the incorporation of the uncertainty from this estimation (including underlying heteroscedasticity) in the final parameter estimates is rarely done; for an exception see the Extended Estimating Equations approach in Basu and Rathouz (2005).
For the multivariate analyses, the choice of estimation approach was informed by the nature of the dependent variable under consideration in each model.
For the multivariate analyses, the choice of estimation approach was informed by the nature of the dependent variable, i.e. utility decrement.
However, the interpretation of experimental recordings is not always adequately informed by the available theory, as highlighted in a recent debate regarding the estimation of repolarization times from electrograms with positive T waves (4, 5, 25).
However, significant under-estimation of large between-farm association frequency was found, when informed by the PND compared with the GBPR, for all regions except the South East and the North West of England.
Informed by the Cig.
However, few of them take into account the geometry of the posterior informed by the data.
2. Be informed by the literature.
It is not informed by the model.
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