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Informed by experiments that showed a Phe19Pro substitution eliminated ion conductance in a planar lipid bilayer, Connelly and colleagues performed MD simulations that predicted a channel-like octadecamer with a collapsed pore [ 112].
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"The diversity of the breeds is something astonishing," he wrote a few years later in "On the Origin of Species" — a work greatly informed by his experiments with the birds.
We develop new theoretical models, informed by our experiments, to analyze how these long-term fitness consequences of parental effects might feed back to change optimal levels of parental care.
The current debate about cognitive penetration is informed by more recent experiments in psychology.
Informed by reaction time experiments, Glucksberg permits us to explore empirically the impact of metaphors that categorize human beings.
He adds that the use of these logos and motifs is readily informed by Warhol's experiments made over 40 years ago".
Many other potential impacting factors for immunogenicity, e.g., initial number of naive T and B cells and number and binding affinity of B-cell epitopes, are designed as integral parts of the model structure; these can also be conceivably informed by conducting appropriate experiments.
There has, for example, been much discussion of what exactly might be traded, and by whom, on a "social stock exchange"—a debate that is being informed by some real-world experiments in places such as Brazil and South Africa.
Much of the current knowledge has been informed by targeted gene deletion experiments and gain-of-functional analysis.
Ideally, policy experiments informed by research would test the impact of interventions to promote uptake of rural posts.
Reassembly requires a synergism of measurement and theory - computational modeling informed by basic connections from experiment should provide realistic models of the complexes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com