Sentence examples for informative variants from inspiring English sources

Focusing analyses on gene-coding regions provides a plausible trade-off between sequencing cost and discovery of informative variants, and may be an attractive study design before genome-wide sequencing study becomes widely available [14], [30], [46], [47], [48].

Often, interesting and informative variants will segregate in a population-specific manner.

For WES analysis, resolution is likely to be limited by the modest numbers of informative variants that can be obtained by exome capture.

Within this 10.7kb region, two different PCR amplicons were designed to incorporate at least 2 informative variants in the HapMap CEPH individuals used in this study.

A linkage disequilibrium (LD -based singLD -basedtide polymorphism (SNP) selection strategy was used to identify a minimal set of informative variants.

Further GWAS and causative mutations studies in the autosomes might be done in the future in order to identify more informative variants for these traits.

Further genotyping revealed that this single informative variant at position 8814 was shared among all samples, confirming their remote common ancestry within X2b1.

Assume that a read aligns to multiple pseudogenomes that straddle an informative variant caused by a SNP.

This approximates the common process of examining alignments only at informative variant positions, while retaining the ability to detect whether two variants fall on the same read.

Analysis of highly-informative variants in selective sets of novel genes complements these candidate SNP and genome-wide association studies, providing improved coverage in high-priority regions based on known tumor biology [16].

Novel population-specific or ancestry-informative variants may be identified, and more eQTLs that contribute to genetic variation of ancestry informative GE may become available.