Under the working assumption of approximate measurement equivalence, informative priors to define elastic constraints are used in these cases.
This study demonstrates that selection of informative subphenotypes to define a homogeneous set of ASD families could be very important in detecting the susceptibility loci in autism.
Testing further informative family members to define the specific haplotype is the aim of our current investigations.
Our tradition of directing 5mC assays towards the analysis of the CpG islands annotated in genome browsers is therefore likely to be suboptimally informative when seeking to define loci where changes in 5mC are associated with transcriptional changes.
For enzymes, it is much more informative to measure defined parameters (such as KD or Ki) that can be compared with computed binding constants, and can be used in modelling complex pathways.
The variability in the predictions of the individual models composing model ensembles, quantified by the ensemble standard deviation, served to define informative confidence intervals.
The mode was considered as most informative and was used to define the timing of each influenza outbreak.
We can use knowledge regarding possible ranges, central values, and measures of dispersion, as well as specific data from separate studies, to define informative prior distributions.
For instance, we could use GWAMA summary statistics to define informative prior distributions for SNP effects, or to (re -weight the SNP contre -weight e.g. similar thethe weighted G-BLUP model propoSNP in (25).
Since it is not known beforehand which gene features are connected to each other, investigators sought to define informative relationships between individual gene patterns to identify many relevant classes of dynamic temporal gene expression patterns.
When researchers in peer review confuse the two dimensions, this can lead to content validity problems that foil attempts to define informative variables and outcome measures, and thus prevent clear trends from emerging.
