Sentence examples for informative tissue from inspiring English sources
Profiling studies of melanoma to date have been inconsistent due to the heterogeneous nature of this malignancy and the limited availability of informative tissue specimens from early stages of disease.
In the informative tissue cores, the intensity of NPC staining was typically pervasive (70% of the epithelial component was positive) and strong (intensity was 2 3) in the DCIS (ductal carcinoma in situ) specimens.
A major roadblock to advances in melanoma therapy has been the relative paucity of informative tissue specimens available for analysis in profiling studies as well as the notoriously heterogeneous nature of this malignancy.
The clustering procedure builds 7 informative tissue array clusters from our data.
First, our results demonstrate the importance of blood as a biologically informative tissue in the elucidation of the obese state.
The TMA contained 1,202 informative tissue cores of NSCLC types and 132 cores of non-neoplastic bronchial/bronchiolar tissue from a cohort of 400 patients.
In pairs with informative normal tissue, sufficient PCR amplification of tumour tissues was considered as informative and MSI was defined as either a marked alteration in repeat length or as a new discrete band above or below the expected allele.
Moreover, single hormone measurements may not be very informative about tissue exposure over time.
The mRNA screen was conducted in transformed LCLs and so it would not be informative about tissue-specific gene expression.[21] Also, SNP coverage across the genome was not complete and so the functional effects of some SNPs for which no proxy was available will be concealed.
Our findings are consistent with another study that found enhancer-associated chromatin marks can be more informative for tissue-specific disease SNP enrichments than DHSs can [ 30].
In the present study, we utilized these renewable anti-LRRK2 monoclonal antibodies with the most informative control tissues to develop robust standardized protocols.
