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This includes the specific research design of the project, the use of pharmaceuticals (especially if they have not yet received full F.D.A. approval), a completely informative subject consent process and, when appropriate, the implementation of a more thorough, campus-wide education project required of all researchers and staff involved in any research employing human subjects.
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The most informative subjects are selected as those with the smallest mean squared estimation error.
Active learning aims to select the most informative subjects for labeling to decrease the amount of labeling requests.
Therefore, to capture how independent and collectively informative subjects' pairs of responses were, we calculated the improvement in accuracy afforded by averaging the responses together.
AI was present in 2 (10%) of 21 informative subjects.
As already pointed out, the increase in power is due to the selection of the most informative subjects.
All informative subjects with deletions extending beyond Xp22.3 had completely skewed X-inactivation, with the deleted X presumably inactive (Table 2).
Baseline core biopsies from four patients contained inadequate tissue for ALDH1 staining and were excluded, leaving a total of 119 informative subjects.
Allelic imbalance at this locus was found in only 10% of informative subjects, suggesting that germline genotype may reflect tumor genotype at this locus.
Pyrosequencing was used as a quick and accurate method for SFP discovery in RT-PCR products amplified from cDNA generated from placental tissues of informative subjects (purebred Meishan or white composite porcine embryos).
The 79 proteins were further analyzed by one-dimensional cluster analysis across all informative study subjects which were readily distinguished from controls as shown in Additional file 7. The 79 BAL proteins are listed by their UniProt identifiers in Additional file 8.
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