Sentence examples for informative offspring from inspiring English sources

Polymorphic markers at each of the candidate loci were studied in a family with 36 informative offspring.

The authors used a selective mapping strategy with a bin set of 14 highly informative offspring from a single full-sib (FS) mapping population for which an AFLP framework map was available.

The minimum number of detected recombinations in our family (1 recombination per 36 informative offspring) would compare to a recombination frequency/genetic distance of ~2.8 cM or a physical distance of ~2.8 Mb.

Our results show a minimum of 6 recombinations (GNAT2; 31 informative offspring) or more than 19.3 Mb distance (Table 2), excluding all the candidate genes as the site of the mutation causing the disease.

It should be pointed out that this strategy was only used if no male recombinations had been observed in a priori informative offspring, meaning that no recombination had been observed in a minimum of 92 (but usually many more) meioses.

The F ratio has degrees of freedom equal to the number of informative parents and the number of records (offspring) minus two times the number of informative parents [ 38]; the latter ranging from 3177 to 3737 depending on the number of marker-informative offspring.

Studies of segregation of each of the 10 candidate loci and clinical disease in informative parents and offspring revealed a number of new candidate gene allele-disease phenotype combinations ("recombinants") in the offspring.

Merging diagnostic information with genotype information to determine informative families yielded 1369 families with complete genotype data for parents and offspring; with at least one genotyped offspring carrying an ASD diagnosis (16 families had more than one genotyped, affected child).

MEST parent-of-origin expression in M. domestica remains undetermined since no informative polymorphisms in parent-offspring duos were found; however, due to the high conservation of imprinting expression at this locus, it is likely that the gene is paternally expressed, as it is in another metatherian, the tammar wallaby [ 8].

Is information always informative?

Markers for which the parents of the reference families were informative were genotyped on the offspring.