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Even if we see any signal in immunofluorescence or Western blot, it will only be informative of whether the Pak-AID is expressed or not.
This assay can be informative of whether the protein alone is pulled down in the ChIP reaction, or if other proteins are also in the eluate, suggesting cross-reactivity or non-specific binding.
c) "Primary validation" part 2 "This assay [western blot of ChIP chromatin] can be informative of whether the protein alone is pulled down in the ChIP reaction, or if other proteins are also in the eluate, suggesting crossreactivity or non-specific binding".
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Taken together, these suggest that DNA duplex stability data should be informative of binding sites; whether a lower or higher DNA duplex stability at specific TF binding sites is more preferable depends largely on the binding preference of the TF, that is, whether the TF binds to the the DNA in a double- or single-strand manner.
The sbv IMPROVER Systems Toxicology challenge was designed to leverage crowdsourcing to determine whether human blood gene expression levels are informative of current and past smoking.
Briefly, this is done by assessing whether the presence of one motif in a sequence is informative about the presence of another motif, and if so whether the distance between the motifs is informative of protein behavior.
In general, results of this study will provide an informative basis whether a combination of traditional face-to-face psychotherapy and web-based depression program is feasible and whether it is more effective compared to regular psychotherapeutic treatment in depressed outpatients in routine care.
A further advantage of supervised inference is that different types of data are informative about whether a functional link may exist, allowing practitioners to integrate data from diverse sources [ 1].
This manuscript addresses the question of whether an individualized assessment of motion may be informative, and whether it may be beneficial with regard to explaining motion-related variance.
With proper precautions and recognition of their limitations, analysis of these samples can be informative regarding whether an exposure to iAs occurred.
It would also be informative to determine whether regression of CIMT and/or the slowing of other cardiovascular outcomes occur in a xenotransplant setting in light of the recent successes in xenotransplantation (28).
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