Thus, the classification of sirtuins based on sequence homology is informative of their biochemical functions, especially acyl group specificity.
Moreover, patterns of DNA methylation at eCGIs are informative of their transcription initiation potential across tissues: the number of tissues where each eCGI is hypomethylated (referred to as 'hypomethylation breadth') and tissue-wise distribution of TSS are strongly positively correlated (Spearman's ρ = 0.73, P < 10−15, Supplementary Material, Fig. S7A).
One of the crucial communication issues that have to be tackled by risk assessors is how to provide a comprehensible and informative characterization of their findings.
Certain businesses find that revenue may not be the most informative indicator of their financial performance.
Before responsive web design became more commonplace, many site owners built a separate, simpler and sometimes less informative version of their site for their mobile web visitors.
However, it is controversial whether such highly idealized models can still be regarded as informative representations of their target systems (for a discussion of caricature models, in particular in economics, see Reiss 2006).
Using Facebook Connect, Intel takes users on a visually beautiful and informative tour of their life on the social network, inviting users to tour their Facebook life as a "journey of visualization that explores who I am". While it is hard not to be taken with the tool just by virtue of it being really cool, I found it inspiring for how we can perhaps teach people about their personal privacy.
While mature microRNAs are much better conserved than the rest of the precursor sequences, they are at the same time less informative because of their short length (≈ 22nt).
When challenging a patient's preferences, health workers should start out by attempting to give a balanced and informative account of their medical perspective on the patient's symptoms and possible causes [ 4, 5].
The evening's guest list, which included Eva Mendez, Natasha Richardson and Anne Hathaway, would suggest otherwise, but the designers said that the style of Hollywood actresses was less informative to their definition of sexiness than it had been in the past.
Given two concepts c 1 and c 2, their shared information, Share (c 1, c 2 ), can be defined as the information content of their most informative common ancestor (CommonAnc(c 1,c 2 )) [ 28]: (8) S h a r e (c 1, c 2 ) = m a x { I C (a ) | a ∈ C o m m o n A n c (c 1, c 2 ) } The most common semantic similarity measures are Resnik [ 29], Lin[ 30] and Jiang [ 31].
