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High-level expression of proteins in animal cells has been very informative in studies of protein and cellular function and in many cases has relied on virus-derived expression vectors.
Our findings indicate that measurements of PfEMP-1-specific antibody levels are likely to be particularly relevant and informative in studies of infant immunity to malaria [37], [38], [39].
Frequencies of Y chromosome haplogroups vary considerably between different geographical regions and ethnic groups, and have turned out to be informative in studies of human evolution and migration.
Understanding the relationship between phenotypic and molecular genetic data sets may be particularly informative in studies of avian taxonomy where plumage characteristics have been historically used to designate subspecies as well as species [ 7].
We hypothesize that the stronger association of MAPT with Familial-PD is indicative of an incompletely penetrant genetic factor, and that pedigrees may be more informative in studies of MAPT and PD.
The phenotype-to-gene results generated from this study will aid the Knockout Mouse Project (Austin et al. 2004) by allowing prospective identification of the behavioral phenotypes most likely to be informative in studies of a given knock-out gene, and will therefore be useful in efforts to guide the intelligent use of costly live mouse derivation and extensive phenotyping.
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Retrospectively, it has been recognised that ORR may not be an informative end point in studies of targeted agents for advanced HCC (Llovet et al, 2008a).
High-throughput microarrays have been informative in genetic studies of osteoporosis, but studies using PBMs and MSCs are not expected to be as useful as studies of osteoclasts, osteoblasts, and osteocytes.
These miRNAs could be informative in studies that compare the efficacy of different treatment methods used for controlling gastro-oesophageal reflux.
5 Because they often have relatively substantial functional consequences and a potentially high incidence in a population, single nucleotide polymorphisms can be very informative and are extensively used in studies of their association with risk for many diseases, including cancer.
While it currently remains unknown if UCP1 in the fat-tailed dunnart truly has a thermogenic function, these two identified sites may prove informative in further studies of UCP1 function.
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