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Nevertheless, the numerous qualitative data in IEDB suggest how to overcome the paucity of informative benchmark data.
In conclusion, our data suggest that expression profiling can serve as an informative benchmark to distinguish different states of primed and naive human pluripotency.
Experimentalists thus could greatly contribute to the further accumulation of informative benchmark data by generating dose-response data at or near half-maximal response levels, expressing antibody-mediated effects as apparent concentration-dependent changes in median effective doses of particular causative agents wherever possible.
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Among the common issues are low concordance between different prediction methods, high variance in performance across samples and the difficulties in constructing realistic and informative performance benchmarks.
We will also discuss an important challenge: the development of adequate benchmarking techniques, informative enough with respect to all potential applications of MSA methods, especially the reconstruction of accurate phylogenies.
Is information always informative?
Performance was assessed in relation to a set of established, reasonably informative, and relatively straightforward to run, benchmarks (so-called micro-benchmarks).
Also, feedback of patient safety culture surveys, combined with benchmark data are found highly informative [ 12].
Nevertheless, any available data on the median effective dose could be embedded within the existing data field for assay comments, so as to facilitate future assembly of benchmark datasets from such maximally informative data.
We have seen that there can be a reasonable extent of variation amongst instances from the same provider for these benchmarks, and the range is more informative than simply selecting a specific best or average result.
In this work we have shown that the exploratory behavior of a small animal, the nematode C. elegans, meets the quantitative benchmarks expected for an optimal, maximally informative strategy.
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CEO of Professional Science Editing for Scientists @ prosciediting.com