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Using highly informative AIMs can reduce the number of markers required, which in turn reduces the time and cost necessary to obtain accurate ancestral information.
Hence, it is important to identify and choose informative AIMs across populations [ 16].
Three of these are the most informative AIMs in differentiating Northern Europeans from Southern Europeans according to a large study [ 22].
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There is a growing interest among geneticists in developing panels of Ancestry Informative Markers (AIMs) aimed at measuring the biogeographical ancestry of individual genomes.
Using ancestry informative markers (AIMs), we aimed to measure the African influences in Spanish populations and to explore whether these might introduce statistical bias in population-based association studies.
The performance of the Structured Association method [23] is highly dependent upon the amount and informativeness of ancestry informative markers (AIMs) [24], and the accuracy of inferred individual ancestry is sensitive to the number of pre-assigned subpopulations, which may not always be satisfactorily resolved [25].
A census-based sample of 800 individuals from Puerto Rico (see Text S1 and Martinez-Cruzado et al. [29] for sample details) was genotyped for a panel of 106 Ancestry Informative Markers (AIMs) selected for their informativeness to differentiate between the three ancestral groups: West Africans, Europeans, and Native Americans.
We used 26 of 136 ancestral informative markers (AIMs) on chromosome 5 for which genotype information for stage 2 subjects was available (Table S3) [19].
Ancestry informative markers (AIMs) are the genetic markers carrying ancestral information for classifying samples from a specific population or various ethnic populations [ 1- 12].
We find that the use of self-identified race and ethnicity (SIRE) exists alongside ancestry informative markers (AIMs) to ascertain genetic ancestry.
Technologically, they deploy a tool called ancestry informative markers (AIMs), which are a collection of genetic sequence variants said to differ in present-day West Africans, East Asians, Europeans, and (ideally Pre-Columbian) Native Americans.
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