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The relatively small number of probes (n = 434, unadjusted P < 0.05) tending towards significant differential expression immediately after exercise suggested that deriving meaningful functional information may be problematic given an expected false discovery rate of approximately 400 probes in this experiment.
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In addition, the counsellee's understanding and retention of the information given may be problematic.
Misclassification of mothers as homemaker or otherwise unemployed on the birth certificate and missing information for paternal occupation may be problematic.
However, obtaining information even about such basic characteristics of non-responders may be problematic.
But that may be problematic, too.
Wound infections may be problematic for physicians.
Accordingly, critical evaluation of the reported results may be problematic.
Whether it will get one may be problematic.
This may be problematic in certain contexts.
Any other use may be problematic.
In addition, the simplified vertical CN distribution may be problematic.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com