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Therefore, our results do not depend on the selection and accuracy of various drug-target prediction algorithms or require structural information concerning compounds and proteins.
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The overwhelming amount of available scholarly literature in the life sciences poses significant challenges to scientists wishing to keep up with important developments related to their research, but also provides a useful resource for the discovery of recent information concerning genes, diseases, compounds and the interactions between them.
In this article, the use of data collected in registration-focused clinical trials to provide information concerning abuse liability of compounds under development is discussed.
CSR curves are useful to compare the chemotype diversity of data sets, however, they do not provide information concerning the distribution of compounds in each chemotype or in the most populated chemotypes [11].
The limited amount of toxicological information concerning many of the compounds detected in stack emissions also complicates the evaluation of the public health impacts of these facilities.
Consequently, direct and indirect quantification of NO and PGI2 may provide information concerning the production of these compounds but do not necessarily indicate inhibition of platelets as the net effect of activating versus inhibitory stimuli remains obscure without a direct assessment of platelet function.
The between-variable correlations and regressions gave further information concerning the mutual relationships of the compounds.
This assay is known to give reliable information concerning the antioxidant ability of the tested compounds [ 41].
Cell type comparisons concerning compound effects on migration.
It was also shown that it is possible to obtain information concerning the behavior of catalysts for deep HDS of refractory compounds, using simple and not expensive model molecules.
Dereplication assays using HPLC play an important role in the search for active compounds from plants, providing rapid access to information concerning both the activity and localization of the activity in complex plant matrices.
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CEO of Professional Science Editing for Scientists @ prosciediting.com