These data indicate that the unassembled sequences represent valuable information that cannot be excluded from the global analysis of the Palomero ESTs, and justify the use of individual GS20 454 reads for the coverage analysis of public databases as described in this work.
As data collection was dependent on chart review, the presence of information bias cannot be excluded.
Nevertheless, the possibility of information bias cannot be excluded in large-scale school-based studies.
In addition, the possibility of information bias cannot be excluded given that some students may not provide valid answers and also may underreport the level of smoking since the data collected are based on a self-administered questionnaire.
Second, due to the sole reliance on self-reported information, it cannot be excluded that strong associations between variables of interest and differences between the clusters are inflated due to shared method variance.
Defined at article 178 of the Swiss code of criminal procedure, a "person asked to provide information," includes "a person who cannot be excluded as the perpetrator of or as a participant in the offence under investigation".
Despite the lack of information regarding other comorbidities, it cannot be excluded that patients from the study by Curtis et al. were at higher risk than ours, resulting in an enhanced effect of therapeutic intervention [ 15].
On the other hand, given a lack of information on genetic polymorphisms, the possibility cannot be excluded that green tea drinking is protective among subgroups of women.
While no information was available on lifestyle, it cannot be excluded that the observed inequalities in survival in early-stage disease throughout follow-up may reflect social differences in smoking cessation following diagnosis.
It should be noted that misuse and abuse of genetic risk information by employers or insurance companies cannot be excluded completely, for employers and insurance companies are susceptible to misinterpretation of genetic test results, and to overstatement of their significance.
