For their derivation, toxicological information, socio-economic information and technical feasibility factors need to be taken into account [13].
We selected the VOCs in this study on the basis of available information and the feasibility of laboratory analysis of VOCs by purge and trap gas chromatography/mass spectrometry (P&T GC/MS) (Bender et al. 1999).
Thus, the sample size was determined as the minimum number required to achieve the pragmatic purpose of the trial (ie, the collection of information such as aggregate values of the outcome results and their variation, safety data and feasibility-related information necessary for designing a future, full-scale clinical trial).
Participants frequently reported good quality of the information for effectiveness and feasibility domains.
This comparison may supply further information about effectiveness and feasibility of this prevention strategy in different populations of the elderly.
The feasibility study provided an opportunity to refine and modify the programme and yielded important information on acceptability and feasibility of the intervention and measurements required for assessing outcomes in a definitive RCT.
We have focused specifically here on discussions of integrating HPV vaccination with other adolescent health services; general information on acceptability and feasibility of introducing HPV vaccination into the public sector is presented elsewhere [ 26].
The aim was to obtain information on safety and feasibility as well as trends in efficacy by determination of overall survival as primary and progression-free survival (PFS), response rate, quality of life (QoL), effects on biological markers of disease (CA 19.9) and angiogenesis (vascular endothelial growth factor and basic fibroblast growth factor) and safety as secondary endpoints.
During the preliminary stages we had to undertake a pilot trial to get information on safety and feasibility of combined chemotherapy with simultaneous treatment of the LMWH enoxaparin in patients with advanced pancreatic cancer who are at high risk of gastrointestinal bleeding due to local cancer spread.
The company said it will be reaching out to officials in the 20 cities over the next few months "to dive deeper into their proposals, request additional information, and evaluate the feasibility of a future partnership".
