Reliable information about the elimination rate of alcohol (ethanol) from blood is often needed in forensic science and legal medicine when alcohol-related crimes, such as drunken driving or drug-related sexual assault are investigated.
Our approach extracted information about both elimination kinetics and exposure trends from biomonitoring data.
For many persistent chemicals, information about human elimination half-lives is scarce (Wolff 1999), and available data exhibit a high degree of uncertainty.
Using three different methods, we were able concurrently to demonstrate the association of I with hCG in humans up to 28 days after injection of radiolabelled hCG i.v. Thus, information about the expected elimination of hCG can be obtained by following the elimination of activity in plasma after injection of I-hCG.
Figure 1 graphically presents results of the optimization procedure for PCB‐52 and PCB‐153 using OFCSD_Only and illustrates how information about exposure and elimination kinetics is represented in the temporal evolution of the age concentration CSD.
Our report provides important genomic information about the virus for measles elimination in Southeast Asia.
The present study demonstrates that CSTD used in combination with exposure data can provide quantitative information about human exposure trends and elimination kinetics that has not been exploited so far.
Toxicokinetics captures information about uptake, distribution, biotransformation, and elimination of a toxicant in an organism, and is important in risk assessment because a chemical needs to enter the organism and reach the site of action in order to elicit an effect.
Selection of proper outliers is of crucial importance because the eliminated regressor vectors contain useful information about the problem, and most probably, improper elimination leads to imperfect results.
