Your English writing platform
Free sign upSuggestions(1)
Exact(3)
BioVU employs novel informatics strategies to de-identify Vanderbilt's comprehensive EMR and link these data to DNA extracted from blood samples obtained through routine clinical care and that would otherwise be discarded.
Taking advantage of these multi-source biomedical data and applying informatics strategies to medicine and care delivery can lead to a next generation precision medicine era [ 1].
Informatics strategies have already been developed which utilize mass spectrometry based approaches in combination with database searches to rapidly identify specific classes of lipids, such as phospholipids [ 16] or PUFA-derived lipid mediators [ 20].
Similar(57)
In coming years, this informatics strategy can be applied on a larger scale, as we develop a more complete empirical database of DNA sequence preferences for human TFs and uDBPs.
Our lipid informatics strategy greatly facilitated interpretation of ob/ob mouse liver lipidomic profiles which resulted in identification of several lipid molecular species.
Using this high quality multi-tissue data set, we applied an integrated informatics strategy which combined targeted bioinformatics and analytical approaches to identify and validate a panel of genes to distinguish normal from cancer tissue.
Results: We present regSNPs, an informatics strategy that integrates several established bioinformatics tools, for prioritizing regulatory SNPs, i.e. the SNPs in the promoter regions that potentially affect phenotype through changing transcription of downstream genes.
Here, we report a new approach for rapidly dissecting a complex phenotype that is based upon the combination of genome-scale growth phenotype data, precisely targeted growth selections, and informatic strategies for abstracting and summarizing data onto coherent biological processes.
This approach relies on a genome-wide bio-informatics strategy to identify cis-acting regulatory modules (CRMs) containing evolutionary conserved clusters of transcription factor binding site motifs that determine high tissue-specific gene expression.
To examine the efficiency with which each platform could design oligos or PCR amplicons to target regions of interest, an identical 5 Mb of genomic sequence (representing the largest commercial capture option at the time) was provided to each vendor for informatics-based targeting using on the vendor's standard informatics design strategy.
Another young woman trained for a career in informatics described her strategy as follows: "Yes, you maybe adjust in a certain sense a little bit.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com