With its modular workflow design and numerous graphical user interfaces, Gene Composer enables researchers to perform all common bio-informatics steps used in modern structure guided protein engineering and synthetic gene engineering.
Because tumor tissues were sequenced without a paired normal from the corresponding patients, additional informatic steps were taken to identify and account for common single nucleotide polymorphisms (SNPS): any SNP present at >0.1 % in Exome Variant Server (NHLBI GO Exome Sequencing Project [ESP], Seattle, WA; URL: http://evs.gs.washington.edu/EVS/) or present in dbSNP was filtered.
Our method, based ideally on at least 20 × and 50 × of NaS and Illumina reads respectively, offers the opportunity to sequence microbial or small eukaryotic genomes in a very short time, even in small facilities, to high accuracy with informatics finishing steps.
Brender [ 21] suggests that the next step in evaluating health informatics sytems should take place during the adaptation phase.
An informatics pipeline involving several steps and analysis platforms was used for analysis (Additional file 2: Figure S1).
In this study, we developed a multi-step biomedical informatics screening (MSBIS) approach leveraging publicly available bioactivity and drug safety data to identify concomitant drugs that mitigate the risks of MCP-induced TD.
Therefore, global sharing of skills in systematics and biodiversity informatics is a requisite step for true globalization of the community and the science.
Because natural languages are used by people universally and allow rich representations that no other language specification can attain, natural language processing (NLP) research is a first step that Informatics should take in order to advance the organization and processing of individual knowledge in case-bases that can be reused.
The availability of such informatics tools represents an important step toward establishing MS imaging as a routine and reliable method in biomedical research.
As a first step, an integrated informatics system and a national integrated surveillance system are being developed, which will facilitate not only communication of data but also the sharing of results.
