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Despite the technical advances, informatics methodologies need to be developed to prioritize thousands of variants for potential causative effects.
While the four areas of research differ in their scientific foundations, they nevertheless share a core set of informatics methodologies, such as data acquisition systems, controlled vocabularies, knowledge representation, simulation and modeling, information retrieval, and signal and image processing, which provide a basis for their intersection.
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Such an investigation can be regarded as a case study using Brain Informatics methodology.
After giving an outline of Brain Informatics methodology, we describe how to design cognitive experiments of mental arithmetic task with multiple difficulty levels for obtaining multiple EEG and fMRI data sources, and how to analyze such data for investigating the spatiotemporal characteristics and flow of human computation processing.
AMB developed the lipid informatics methodology and drafted the manuscript.
LY developed the lipid informatics methodology, performed data analyses, and drafted the manuscript.
Using a newly devised chemocentric informatics methodology for drug discovery integration showed that selective estrogen receptor modulators are putative ligands of 5-HT6 receptors [ 32].
Translational bioinformatics is an emerging field that focuses on applying informatics methodology to the increasing amount of biomedical and genomic data in order to generate knowledge for clinical applications.
Informatic methodologies are being applied successfully to analyze the complexity of the genome.
Coupled with a multitude of bio-informatic methodologies publicly available on the Internet and made available by consortia of laboratories, investigators can now mine these databases to explore the presence of unique gene sets, the distribution patterns of gene expression, and the possible existence of unique structural features in predicted gene products.
Here we use an informatic methodology to uncover the large-scale architecture of the cytokine networks that connect immune and non-immune cells.
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technology methodologies
informatics process
computer based methodologies
computational methodologies
informatics practice
information methodologies
computer methodologies
informatics design
informatics approach
it methodologies
computerised methodologies
informatics survey
informatics methodology
data processing methodologies
computing methodologies
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